Duke Nukem appeared in the 1991 video game of the same name and several sequels. He is an action hero that defends earth from invading aliens. He wields countless types of weapons, and is a lady's man since all the women just adore him in his video games, and his egotism is like a shield.
During the PVP fight at Planet Doom, Duke Nukem can be seen launching rockets at other players before being shot by Aech.
When driving around the battlefield, Wade loads up the Railgun from Duke Nukem Forever.